THCV is a lesser-known cannabinoid with many potential health benefits. It has been shown to have anti-inflammatory effects, help regulate blood sugar levels, and promote bone growth. THCV may also support healthy weight loss, improve heart health, and reduce anxiety. However, more research is needed before recommending it to patients.
When you buy THCV, it has anti-inflammatory properties and has been shown to inhibit the production of specific inflammatory molecules. This includes reducing the amount of interleukin (IL)-6 and IL-8 released from lung epithelial cells.
The anti-inflammatory effect of THCV is believed to be primarily mediated through CB2 receptors. However, it has been shown that THCV can also suppress signs of inflammation and pain through several other mechanisms.
In addition, THCV has been shown to alleviate the symptoms of obesity and diabetes in mice by enhancing insulin sensitivity. It was also found to be a potent inhibitor of inflammatory enzymes.
One of the most exciting aspects of research into cannabis compounds is their potential to be used as neuroprotective agents. The endocannabinoid system (ECS) plays a critical role in the pathophysiology of many neurological disorders. It is currently attracting significant interest in developing ECS-targeted therapeutics for brain damage.
The plant Cannabis sativa contains over 60 different pharmacologically active cannabinoids, including D9THC and CBD. These compounds have been found to protect brain cells from oxidative stress, inflammation, and apoptosis in animal models of PD and AD.
Using a mouse model of THCV-induced dyskinesia, we found that the phytocannabinoid D9-THCV protected L-DOPA-treated mice from the onset of the dyskinetic symptoms. Furthermore, concentration-dependent protection was observed against the oxidative stress of hydrogen peroxide (H2O2) in primary hippocampal neurons.
Reduces Nausea and Vomiting
Nausea is a common yet often disabling symptom of medical treatment. Despite modern pharmacological interventions, nausea (acute, delayed, and anticipatory) remains problematic.
Although current anti-emetic medications effectively control most CINV, it can be a distressing and unrelenting symptom. Patients are left with a lingering sensation of nausea, often leading to an inability to eat and drink.
THCV appears to reduce nausea by stimulating appetite and reducing intestinal motility. This is likely the result of its ability to bind to CB1 cannabinoid receptors in the brain that regulate nausea.
Lowers Blood Sugar Levels
THCV is a non-psychoactive cannabinoid that has been shown to lower blood sugar levels in rodents. It also decreases food intake and increases energy expenditure, thereby increasing satiety.
It has also improved insulin sensitivity and glucose tolerance in dietary-induced obese (DIO) and genetically obese (ob/ob) mice. It also significantly reduced liver triglycerides and increased hepatic ATP content.
THCV has pharmacological properties that differ from CB1 inverse agonists such as rimonabant, which improved type 2 diabetes and dyslipidemia but was discontinued due to adverse psychiatric effects. Conversely, THCV produces therapeutic metabolic effects in two obesity mouse models with a more profound leptin-based effect than on glucose or insulin.
Reduces Panic Attacks
If you’re dealing with anxiety disorders like PTSD or OCD, THCV may be your answer. Research has shown that THCV calms the sympathetic nervous system and inhibits the fight or flight response, eradicating panic attacks. Moreover, THCV has also been found to suppress appetite in mice, but the results of human trials are more limited. Lastly, THCV has been found to reduce the symptoms of certain psychiatric diseases, such as schizophrenia, and improves cognitive performance. It may also promote sleep, significantly impacting your quality of life and overall well-being. For these reasons, it’s no wonder THCV is quickly becoming one of the most popular strains on the market today.